Abraham Whistler fathered a daughter out of wedlock or before marriage. This daughter was Abigail Whistler who eventually tracked down her natural father and asked to be trained as a vampire hunter. Whistler trained her, although he trained her separately from Blade who was totally unaware that Whistler had any protegees other than himself.
Whistler also set Abigail up as the leader of one of the many Nightstalker units he had secretly founded. It is assumed that these units were set up because one man (or half-vampire) is not enough to destroy an entire species. Also, since Blade is not immortal (he will eventually die from old age), Whistler did not want the war to die with him.
Among this team of Nightstalkers is Hannibal King. Once a former vampire and the chew toy for Danica Talos, Abigail met him in a club one night and turned him back. Ever since they haven't parted ways. Hedges, he would be there weapons man and engineer. Sommerfield is the computer and chemist, she's blind and her daughter stays with them. Then there's Dex he's another of the field guys like Abigail and Hannibal.
There are other units of the team, they work in sleeper cells. Abigail herself is an expert archer. Her weapons of choice are her compound bow, and her uv arc. It's a hand held weapon form like a bow but there's a lazer of UV light that can cut through nearly anything.
Her father's now dead, her team disbanded and most dead. Supposedly Drake (The father of all vampires) was terminated by Blade. It was supposed to wipe out all vampire kind, but that's yet to be determined.
((I am not Jessica Biel, promise you I'm not. I don't own Abigail Whistler, she's just a character, in a movie that I really liked.))